Acid phosphatase activity of liver homogenates and its relation to drug activity in rats infected with Mycobacterium lepraemurium.
نویسندگان
چکیده
Chatterjee (8) and Rees and Waters (~ I ) suggested the value of examination of acid phosphatase activity in experimental and human leprosy. Hence certain we)) known anti mycobacterial agents like isonicotin ic acid hydrazide ( isoniazid, INH ), 2-ethylisothionicotinamide ( E t h ion a m ide , Trescatyl, 1314TH, Thioamid ), 4, 4'-diaminodiph en yl sulfon e ( DDS ), l(p-N,_ dimethylaminophenyl) 3 (p-n-butoxyphenylthiourea (Su. 1906) and p-acetylaminobenzaldehyde th iose m ica rb az on e (Conteben, TBI/ 698) were reassayed in experimental murine leprosy of ra ts with a view to determining if there is any relation between ' organ weights, necropsy findin gs, histopathologic findings and acid phosphatase activity.
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ورودعنوان ژورنال:
- International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
دوره 38 3 شماره
صفحات -
تاریخ انتشار 1970